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: Multiple Sequence Alignment (MSA)
Upload MSA file
Retrieve from AlphaFoldDB
Choose MSA file
Accepted formats:
FASTA
,
A3M
,
A2M
. Ensure the first sequence is the
ungapped query
.
You may generate your alignment using
ColabFold
or
download an example MSA
.
Add a list of mutations
Choose CSV file
File must be a
.csv
with two columns:
Mutation
and
Phenotype
, separated by a comma.
Mutation, Phenotype
A23T, Increased Stability
G45D, Decreased Activity
Visualize predictions on the 3D structure and compute structure-informed scores
Retrieve from AlphaFoldDB
Upload custom PDB
Choose PDB file
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Load an Example Protein